Exelixis (EXEL) Competitors $36.70 -0.14 (-0.38%) Closing price 03/28/2025 04:00 PM EasternExtended Trading$37.03 +0.33 (+0.90%) As of 03/28/2025 07:15 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock EXEL vs. ALNY, BIIB, UTHR, BMRN, INCY, NBIX, EXAS, RGEN, HALO, and MDGLShould you be buying Exelixis stock or one of its competitors? The main competitors of Exelixis include Alnylam Pharmaceuticals (ALNY), Biogen (BIIB), United Therapeutics (UTHR), BioMarin Pharmaceutical (BMRN), Incyte (INCY), Neurocrine Biosciences (NBIX), Exact Sciences (EXAS), Repligen (RGEN), Halozyme Therapeutics (HALO), and Madrigal Pharmaceuticals (MDGL). These companies are all part of the "biotechnology" industry. Exelixis vs. Alnylam Pharmaceuticals Biogen United Therapeutics BioMarin Pharmaceutical Incyte Neurocrine Biosciences Exact Sciences Repligen Halozyme Therapeutics Madrigal Pharmaceuticals Exelixis (NASDAQ:EXEL) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their profitability, community ranking, valuation, dividends, institutional ownership, risk, earnings, analyst recommendations and media sentiment. Does the MarketBeat Community favor EXEL or ALNY? Alnylam Pharmaceuticals received 538 more outperform votes than Exelixis when rated by MarketBeat users. Likewise, 76.28% of users gave Alnylam Pharmaceuticals an outperform vote while only 68.58% of users gave Exelixis an outperform vote. CompanyUnderperformOutperformExelixisOutperform Votes62068.58% Underperform Votes28431.42% Alnylam PharmaceuticalsOutperform Votes115876.28% Underperform Votes36023.72% Does the media refer more to EXEL or ALNY? In the previous week, Alnylam Pharmaceuticals had 11 more articles in the media than Exelixis. MarketBeat recorded 47 mentions for Alnylam Pharmaceuticals and 36 mentions for Exelixis. Exelixis' average media sentiment score of 1.05 beat Alnylam Pharmaceuticals' score of 0.80 indicating that Exelixis is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Exelixis 20 Very Positive mention(s) 5 Positive mention(s) 6 Neutral mention(s) 1 Negative mention(s) 0 Very Negative mention(s) Positive Alnylam Pharmaceuticals 23 Very Positive mention(s) 8 Positive mention(s) 10 Neutral mention(s) 3 Negative mention(s) 1 Very Negative mention(s) Positive Do insiders and institutionals hold more shares of EXEL or ALNY? 85.3% of Exelixis shares are held by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. 2.9% of Exelixis shares are held by insiders. Comparatively, 1.5% of Alnylam Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth. Do analysts prefer EXEL or ALNY? Exelixis currently has a consensus price target of $37.59, suggesting a potential upside of 2.42%. Alnylam Pharmaceuticals has a consensus price target of $312.30, suggesting a potential upside of 16.33%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than Exelixis.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Exelixis 1 Sell rating(s) 8 Hold rating(s) 11 Buy rating(s) 0 Strong Buy rating(s) 2.50Alnylam Pharmaceuticals 1 Sell rating(s) 4 Hold rating(s) 20 Buy rating(s) 0 Strong Buy rating(s) 2.76 Is EXEL or ALNY more profitable? Exelixis has a net margin of 24.04% compared to Alnylam Pharmaceuticals' net margin of -12.37%. Exelixis' return on equity of 23.52% beat Alnylam Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Exelixis24.04% 23.52% 17.95% Alnylam Pharmaceuticals -12.37%N/A -6.83% Which has more volatility & risk, EXEL or ALNY? Exelixis has a beta of 0.57, indicating that its share price is 43% less volatile than the S&P 500. Comparatively, Alnylam Pharmaceuticals has a beta of 0.39, indicating that its share price is 61% less volatile than the S&P 500. Which has stronger valuation & earnings, EXEL or ALNY? Exelixis has higher earnings, but lower revenue than Alnylam Pharmaceuticals. Alnylam Pharmaceuticals is trading at a lower price-to-earnings ratio than Exelixis, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioExelixis$2.17B4.74$521.27M$1.7720.73Alnylam Pharmaceuticals$2.25B15.53-$278.16M-$2.17-123.71 SummaryExelixis and Alnylam Pharmaceuticals tied by winning 9 of the 18 factors compared between the two stocks. Remove Ads Get Exelixis News Delivered to You Automatically Sign up to receive the latest news and ratings for EXEL and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart EXEL vs. The Competition Export to ExcelMetricExelixisBiological Products IndustryMedical SectorNASDAQ ExchangeMarket Cap$10.27B$3.03B$5.63B$7.83BDividend YieldN/A1.54%4.57%4.01%P/E Ratio20.7328.9323.3318.67Price / Sales4.74429.70388.4691.01Price / Cash18.22168.6838.1634.64Price / Book4.583.926.894.23Net Income$521.27M-$71.95M$3.20B$247.15M7 Day Performance-0.70%-5.55%-2.98%-2.17%1 Month Performance-5.14%-11.96%1.63%-5.68%1 Year Performance54.66%-27.81%9.44%-0.74% Exelixis Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)EXELExelixis4.5269 of 5 stars$36.70-0.4%$37.59+2.4%+54.7%$10.27B$2.17B20.731,220Upcoming EarningsAnalyst ForecastAnalyst RevisionNews CoveragePositive NewsALNYAlnylam Pharmaceuticals4.2386 of 5 stars$288.32+1.8%$312.30+8.3%+79.6%$37.36B$2.25B-133.002,230BIIBBiogen4.9008 of 5 stars$141.40+0.4%$213.33+50.9%-35.8%$20.70B$9.68B12.648,720Positive NewsUTHRUnited Therapeutics4.9332 of 5 stars$318.65+1.8%$388.25+21.8%+33.6%$14.31B$2.88B13.99980Insider TradeShort Interest ↓Positive NewsBMRNBioMarin Pharmaceutical4.9247 of 5 stars$71.68+0.6%$94.00+31.1%-18.2%$13.67B$2.85B32.583,401Options VolumeINCYIncyte4.6784 of 5 stars$62.66+1.2%$74.88+19.5%+6.4%$12.10B$4.24B231.542,617Positive NewsNBIXNeurocrine Biosciences4.9212 of 5 stars$114.74+2.5%$165.24+44.0%-18.0%$11.43B$2.36B34.841,200Analyst ForecastNews CoveragePositive NewsEXASExact Sciences4.4935 of 5 stars$47.00+3.0%$70.83+50.7%-36.8%$8.73B$2.76B-8.436,400Analyst ForecastNews CoveragePositive NewsRGENRepligen4.7383 of 5 stars$144.36+3.1%$178.64+23.7%-27.5%$8.10B$634.44M-283.042,020HALOHalozyme Therapeutics4.2592 of 5 stars$63.81-2.1%$62.78-1.6%+56.9%$7.88B$1.02B18.60390Positive NewsMDGLMadrigal Pharmaceuticals3.4572 of 5 stars$344.48+0.8%$378.44+9.9%+22.8%$7.61B$180.13M-13.7490 Remove Ads Related Companies and Tools Related Companies Alnylam Pharmaceuticals Alternatives Biogen Alternatives United Therapeutics Alternatives BioMarin Pharmaceutical Alternatives Incyte Alternatives Neurocrine Biosciences Alternatives Exact Sciences Alternatives Repligen Alternatives Halozyme Therapeutics Alternatives Madrigal Pharmaceuticals Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:EXEL) was last updated on 3/29/2025 by MarketBeat.com Staff From Our PartnersA market crash is coming—here’s whenThe stock market cycle I've used to identify the most likely day of the next market crash is the exact same in...Chaikin Analytics | SponsoredYour Wealth is Under AttackPlease don't wait—this is your moment to take action. 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