Exelixis (EXEL) Competitors $38.31 -0.16 (-0.42%) Closing price 08/15/2025 04:00 PM EasternExtended Trading$38.33 +0.02 (+0.05%) As of 08/15/2025 07:56 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock EXEL vs. BIIB, INCY, UTHR, NBIX, BMRN, MDGL, EXAS, HALO, RGEN, and IONSShould you be buying Exelixis stock or one of its competitors? The main competitors of Exelixis include Biogen (BIIB), Incyte (INCY), United Therapeutics (UTHR), Neurocrine Biosciences (NBIX), BioMarin Pharmaceutical (BMRN), Madrigal Pharmaceuticals (MDGL), Exact Sciences (EXAS), Halozyme Therapeutics (HALO), Repligen (RGEN), and Ionis Pharmaceuticals (IONS). These companies are all part of the "biotechnology" industry. Exelixis vs. Its Competitors Biogen Incyte United Therapeutics Neurocrine Biosciences BioMarin Pharmaceutical Madrigal Pharmaceuticals Exact Sciences Halozyme Therapeutics Repligen Ionis Pharmaceuticals Biogen (NASDAQ:BIIB) and Exelixis (NASDAQ:EXEL) are both large-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their profitability, earnings, valuation, risk, institutional ownership, dividends, analyst recommendations and media sentiment. Do analysts rate BIIB or EXEL? Biogen presently has a consensus target price of $185.74, suggesting a potential upside of 34.01%. Exelixis has a consensus target price of $44.06, suggesting a potential upside of 15.00%. Given Biogen's higher possible upside, equities analysts clearly believe Biogen is more favorable than Exelixis.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Biogen 0 Sell rating(s) 21 Hold rating(s) 11 Buy rating(s) 0 Strong Buy rating(s) 2.34Exelixis 1 Sell rating(s) 8 Hold rating(s) 13 Buy rating(s) 0 Strong Buy rating(s) 2.55 Which has more risk and volatility, BIIB or EXEL? Biogen has a beta of 0.13, meaning that its stock price is 87% less volatile than the S&P 500. Comparatively, Exelixis has a beta of 0.29, meaning that its stock price is 71% less volatile than the S&P 500. Is BIIB or EXEL more profitable? Exelixis has a net margin of 27.01% compared to Biogen's net margin of 15.31%. Exelixis' return on equity of 27.47% beat Biogen's return on equity.Company Net Margins Return on Equity Return on Assets Biogen15.31% 13.85% 8.32% Exelixis 27.01%27.47%20.88% Which has better earnings and valuation, BIIB or EXEL? Biogen has higher revenue and earnings than Exelixis. Biogen is trading at a lower price-to-earnings ratio than Exelixis, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioBiogen$9.68B2.10$1.63B$10.4613.25Exelixis$2.23B4.62$521.27M$2.0818.42 Do insiders and institutionals hold more shares of BIIB or EXEL? 87.9% of Biogen shares are held by institutional investors. Comparatively, 85.3% of Exelixis shares are held by institutional investors. 0.2% of Biogen shares are held by insiders. Comparatively, 2.8% of Exelixis shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth. Does the media refer more to BIIB or EXEL? In the previous week, Biogen had 20 more articles in the media than Exelixis. MarketBeat recorded 38 mentions for Biogen and 18 mentions for Exelixis. Exelixis' average media sentiment score of 1.16 beat Biogen's score of 1.06 indicating that Exelixis is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Biogen 22 Very Positive mention(s) 1 Positive mention(s) 8 Neutral mention(s) 3 Negative mention(s) 0 Very Negative mention(s) Positive Exelixis 11 Very Positive mention(s) 1 Positive mention(s) 5 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive SummaryExelixis beats Biogen on 10 of the 16 factors compared between the two stocks. Get Exelixis News Delivered to You Automatically Sign up to receive the latest news and ratings for EXEL and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding EXEL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart EXEL vs. The Competition Export to ExcelMetricExelixisMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$10.31B$3.14B$5.72B$9.79BDividend YieldN/A2.22%3.91%4.13%P/E Ratio18.4221.0331.1425.06Price / Sales4.62285.40416.7890.80Price / Cash19.8942.6136.7858.67Price / Book5.078.659.086.18Net Income$521.27M-$54.65M$3.26B$265.11M7 Day Performance1.56%6.56%7.39%4.22%1 Month Performance-14.62%4.82%4.22%0.77%1 Year Performance45.39%15.81%30.30%24.69% Exelixis Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)EXELExelixis4.8717 of 5 stars$38.31-0.4%$44.06+15.0%+45.4%$10.31B$2.23B18.421,147Positive NewsAnalyst ForecastBIIBBiogen4.8569 of 5 stars$129.60+1.2%$185.63+43.2%-31.4%$18.98B$9.68B12.387,605Positive NewsAnalyst ForecastAnalyst RevisionINCYIncyte4.6519 of 5 stars$81.52+2.9%$81.20-0.4%+39.8%$15.92B$4.24B18.532,617Trending NewsUTHRUnited Therapeutics4.9133 of 5 stars$299.78-0.2%$379.69+26.7%-2.4%$13.52B$2.88B11.701,305Positive NewsAnalyst ForecastNBIXNeurocrine Biosciences4.8465 of 5 stars$128.03+3.3%$160.90+25.7%-8.4%$12.66B$2.36B37.771,800Positive NewsBMRNBioMarin Pharmaceutical4.9979 of 5 stars$56.90+0.2%$93.17+63.7%-35.7%$10.91B$2.85B16.863,040Positive NewsMDGLMadrigal Pharmaceuticals3.7067 of 5 stars$356.41+2.0%$439.71+23.4%+47.5%$7.88B$180.13M-27.6190Trending NewsAnalyst ForecastInsider TradeEXASExact Sciences4.8774 of 5 stars$41.54+1.5%$67.43+62.3%-22.4%$7.86B$2.76B-7.657,000News CoverageAnalyst ForecastHALOHalozyme Therapeutics4.6673 of 5 stars$63.14+0.4%$66.56+5.4%+13.2%$7.77B$1.02B14.43390Positive NewsInsider TradeRGENRepligen4.8388 of 5 stars$119.51+6.8%$169.45+41.8%-15.7%$6.71B$634.44M-477.021,778News CoveragePositive NewsInsider TradeIONSIonis Pharmaceuticals4.6077 of 5 stars$40.49-0.9%$58.43+44.3%-5.8%$6.45B$705M-22.001,069Analyst Upgrade Related Companies and Tools Related Companies Biogen Alternatives Incyte Alternatives United Therapeutics Alternatives Neurocrine Biosciences Alternatives BioMarin Pharmaceutical Alternatives Madrigal Pharmaceuticals Alternatives Exact Sciences Alternatives Halozyme Therapeutics Alternatives Repligen Alternatives Ionis Pharmaceuticals Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:EXEL) was last updated on 8/17/2025 by MarketBeat.com Staff From Our PartnersTrump’s national nightmare is herePorter Stansberry and Jeff Brown say a new U.S. national emergency is already underway — and it could trigger ...Porter & Company | SponsoredAlex’s “Next Magnificent Seven” stocksThe original “Magnificent Seven” turned $7K into $1.18 million. 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