Puma Biotechnology (PBYI) Stock Chart & Stock Price History $5.25 +0.03 (+0.57%) Closing price 08/22/2025 04:00 PM EasternExtended Trading$5.26 +0.01 (+0.29%) As of 08/22/2025 06:28 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Puma Biotechnology Stock Price Performance The Puma Biotechnology (PBYI) stock chart highlights key performance trends across multiple timeframes. Over the last 12 months, the stock's price has increased 106.69%, with a year-to-date return of 72.13%. In the past month, the stock has increased 52.17%, reflecting recent market activity. As of the latest close, Puma Biotechnology traded at $5.25 with a market cap of $264.45 million and volume of 669,767 shares. Five years ago, the stock traded at $10.93, representing a 51.97% decrease over that period. At the time, it had a market cap of $433.27 million and a volume of 643,470 shares. Receive PBYI Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Puma Biotechnology and its competitors with MarketBeat's FREE daily newsletter. Email Address 5 Day Performance+4.79%1 Month Performance+52.17%3 Month Performance+62.54%Year-To-Date Performance+72.13%1 Year Performance+106.69%5 Year Performance-51.97% PBYI Stock Chart for Saturday, August, 23, 2025 PBYI Chart by TradingView Puma Biotechnology Stock Price History Daily Weekly Monthly Yearly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year 3 Year 5 Year Time Frame Start Date End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization08/22/2025$5.22$5.25+0.57%$5.37$5.04669,767 shs$264.45 million08/21/2025$5.11$5.22+2.15%$5.40$5.07807,250 shs$262.93 million08/20/2025$5.09$5.11+0.39%$5.22$4.96685,036 shs$257.39 million08/19/2025$5.01$5.09+1.60%$5.32$4.841.26 million shs$256.39 million08/18/2025$5.73$5.01-12.57%$6.07$4.811.66 million shs$252.35 million08/15/2025$5.32$5.73+7.71%$5.81$5.291.02 million shs$288.62 million08/14/2025$5.30$5.32+0.38%$5.45$5.08634,580 shs$267.97 million08/13/2025$4.87$5.30+8.83%$5.44$4.871.72 million shs$266.96 million08/12/2025$4.85$4.87+0.41%$4.98$4.661.64 million shs$245.30 million08/11/2025$3.69$4.85+31.44%$5.06$3.713.94 million shs$244.29 million Get the Latest News and Ratings for PBYI and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Puma Biotechnology and its competitors with MarketBeat's FREE daily newsletter. 08/08/2025$3.29$3.69+12.16%$3.75$3.051.35 million shs$183.14 million08/07/2025$3.25$3.29+1.23%$3.32$3.22501,035 shs$163.28 million08/06/2025$3.22$3.25+0.93%$3.27$3.13340,854 shs$161.30 million08/05/2025$3.18$3.22+1.26%$3.25$3.05357,505 shs$159.81 million08/04/2025$3.07$3.18+3.58%$3.22$3.04279,455 shs$157.82 million08/01/2025$3.11$3.07-1.29%$3.10$3.03230,766 shs$152.36 million07/31/2025$3.16$3.11-1.58%$3.17$3.07293,253 shs$154.35 million07/30/2025$3.18$3.16-0.63%$3.29$3.16206,065 shs$156.83 million07/29/2025$3.34$3.18-4.79%$3.36$3.18323,932 shs$157.82 million07/28/2025$3.28$3.34+1.83%$3.41$3.32347,986 shs$165.77 million07/25/2025$3.40$3.28-3.53%$3.40$3.23300,286 shs$162.79 million07/24/2025$3.45$3.40-1.45%$3.48$3.39158,704 shs$168.74 million07/23/2025$3.47$3.45-0.58%$3.52$3.40304,657 shs$171.22 million07/22/2025$3.41$3.47+1.76%$3.52$3.40336,421 shs$172.22 million Related Companies ADMA Biologics Stock Chart CytomX Therapeutics Stock Chart Entrada Therapeutics Stock Chart Tilray Brands Stock Chart Arcus Biosciences Stock Chart LENZ Therapeutics Stock Chart Zymeworks Stock Chart Spyre Therapeutics Stock Chart Upstream Bio Stock Chart Stoke Therapeutics Stock Chart Receive PBYI Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Puma Biotechnology and its competitors with MarketBeat's FREE daily newsletter. 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