Spero Therapeutics (SPRO) Stock Chart & Stock Price History $0.83 -0.01 (-0.68%) Closing price 02/21/2025 04:00 PM EasternExtended Trading$0.80 -0.03 (-3.37%) As of 02/21/2025 04:09 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrends Spero Therapeutics Stock Price Performance 5 Day Performance+1.96%1 Month Performance-4.92%3 Month Performance-28.36%6 Month Performance-38.44%Year-To-Date Performance-19.32%1 Year Performance-43.47% Receive SPRO Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spero Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address SPRO Stock Chart for Saturday, February, 22, 2025 SPRO Chart by TradingView Spero Therapeutics Stock Price History Daily Weekly Monthly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year Time Frame * Start Date * End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization02/21/2025$0.84$0.83-0.68%$0.84$0.8182,071 shs$45.31 million02/20/2025$0.84$0.84-0.13%$0.84$0.8360,500 shs$45.62 million02/19/2025$0.82$0.84+2.03%$0.84$0.82224,155 shs$45.68 million02/18/2025$0.82$0.82+0.75%$0.86$0.8282,607 shs$44.77 million02/17/2025$0.82$0.82$0.82$0.8090,543 shs$44.43 million02/14/2025$0.82$0.82-0.21%$0.82$0.8090,543 shs$44.43 million02/13/2025$0.81$0.82+1.28%$0.83$0.8160,993 shs$44.53 million02/12/2025$0.82$0.81-1.81%$0.82$0.8047,955 shs$43.97 million02/11/2025$0.80$0.82+3.19%$0.84$0.7960,505 shs$44.78 million02/10/2025$0.82$0.80-2.75%$0.82$0.79141,911 shs$44.62 million Get the Latest News and Ratings for SPRO and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Spero Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 02/07/2025$0.86$0.82-5.20%$0.86$0.81147,287 shs$44.62 million02/06/2025$0.88$0.86-1.56%$0.90$0.85224,011 shs$47.07 million02/05/2025$0.75$0.88+16.44%$0.95$0.751.49 million shs$47.81 million02/04/2025$0.80$0.75-6.19%$0.82$0.74677,405 shs$41.06 million02/03/2025$0.86$0.80-6.27%$0.85$0.79443,856 shs$43.77 million01/31/2025$0.87$0.86-1.54%$0.88$0.8567,114 shs$46.70 million01/30/2025$0.86$0.87+1.17%$0.87$0.84149,583 shs$47.43 million01/29/2025$0.87$0.86-1.46%$0.87$0.8550,744 shs$46.88 million01/28/2025$0.86$0.87+1.45%$0.88$0.8577,180 shs$47.57 million01/27/2025$0.87$0.86-0.88%$0.90$0.8659,690 shs$46.89 million01/24/2025$0.87$0.87-0.36%$0.88$0.85170,867 shs$47.31 million01/23/2025$0.87$0.87-0.37%$0.92$0.86117,273 shs$47.48 million01/22/2025$0.90$0.87-2.41%$0.94$0.86187,002 shs$47.65 million01/21/2025$0.91$0.90-1.58%$0.94$0.87266,411 shs$48.83 million Related Companies ProQR Therapeutics Stock Price Chart Actuate Therapeutics Stock Price Chart Aclaris Therapeutics Stock Price Chart Inhibikase Therapeutics Stock Price Chart scPharmaceuticals Stock Price Chart Lyell Immunopharma Stock Price Chart Alector Stock Price Chart Innate Pharma Stock Price Chart Greenwich LifeSciences Stock Price Chart MacroGenics Stock Price Chart Receive SPRO Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spero Therapeutics and its competitors with MarketBeat's FREE daily newsletter. This page (NASDAQ:SPRO) was last updated on 2/22/2025 by MarketBeat.com Staff From Our PartnersNvidia’s Next Big Move Comes on Feb. 26Nvidia isn't the only company that benefits greatly from these earnings calls. That's because a handful of ...Weiss Ratings | SponsoredA strange twist 500 miles from WashingtonEnergy is life. And this year, it could also make national heroes out of President Trump and VP Vance. ...Porter & Company | SponsoredMajor AI announcement for 2025BIG NEWS: “Market Wizard” Larry Benedict Releases a Whole New Way to Trade AI StocksBrownstone Research | Sponsored Adding Choose a watchlist: Watchlist Adding You have already added five stocks to your watchlist. Upgrade to MarketBeat All Access to add more stocks to your watchlist. Adding Spero Therapeutics, Inc. Please log in to your account or sign up in order to add this asset to your watchlist. Share Spero Therapeutics With A Colleague Link copied to clipboard. 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