Trending NewsTrending NewsMost-Downgraded StocksMost-DowngradedNASDAQ:VRTX Vertex Pharmaceuticals (VRTX) Stock Price, News & Analysis $374.98 -97.29 (-20.60%) Closing price 08/5/2025 04:00 PM EasternExtended Trading$375.62 +0.64 (+0.17%) As of 09:08 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock About Vertex Pharmaceuticals Stock (NASDAQ:VRTX) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get Vertex Pharmaceuticals alerts:Sign Up Key Stats Today's Range$373.19▼$414.8850-Day Range$374.98▼$479.5352-Week Range$373.19▼$519.88Volume10.72 million shsAverage Volume1.17 million shsMarket Capitalization$96.29 billionP/E Ratio26.80Dividend YieldN/APrice Target$495.21Consensus RatingModerate Buy Company Overview Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor. The company's pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial. In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts. Read More Vertex Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks98th Percentile Overall ScoreVRTX MarketRank™: Vertex Pharmaceuticals scored higher than 98% of companies evaluated by MarketBeat, and ranked 60th out of 1,841 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.3 / 5Analyst RatingModerate Buy Consensus RatingVertex Pharmaceuticals has received a consensus rating of Moderate Buy. The company's average rating score is 2.50, and is based on 11 buy ratings, 14 hold ratings, and no sell ratings.Amount of Analyst CoverageVertex Pharmaceuticals has been the subject of 11 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Vertex Pharmaceuticals' stock forecast and price target. Earnings and Valuation2.5 / 5Proj. Earnings Growth12.03% Earnings GrowthEarnings for Vertex Pharmaceuticals are expected to grow by 12.03% in the coming year, from $15.63 to $17.51 per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Vertex Pharmaceuticals is 26.80, which means that it is trading at a less expensive P/E ratio than the market average P/E ratio of about 27.90.Price to Earnings Ratio vs. SectorThe P/E ratio of Vertex Pharmaceuticals is 26.80, which means that it is trading at a less expensive P/E ratio than the Medical sector average P/E ratio of about 28.92.Price to Book Value per Share RatioVertex Pharmaceuticals has a P/B Ratio of 5.88. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities. Short Interest3.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted1.64% of the float of Vertex Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverVertex Pharmaceuticals has a short interest ratio ("days to cover") of 2.8, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Vertex Pharmaceuticals has recently increased by 4,237.47%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldVertex Pharmaceuticals does not currently pay a dividend.Dividend GrowthVertex Pharmaceuticals does not have a long track record of dividend growth. Sustainability and ESG3.3 / 5Environmental Score-3.12 Percentage of Shares Shorted1.64% of the float of Vertex Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverVertex Pharmaceuticals has a short interest ratio ("days to cover") of 2.8, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Vertex Pharmaceuticals has recently increased by 4,237.47%, indicating that investor sentiment is decreasing significantly. News and Social Media3.8 / 5News Sentiment0.88 News SentimentVertex Pharmaceuticals has a news sentiment score of 0.88. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.45 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 61 news articles for Vertex Pharmaceuticals this week, compared to 31 articles on an average week.Search Interest42 people have searched for VRTX on MarketBeat in the last 30 days. This is an increase of 56% compared to the previous 30 days.MarketBeat Follows20 people have added Vertex Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is an increase of 25% compared to the previous 30 days. Company Ownership2.5 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Vertex Pharmaceuticals insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $22,084.00 in company stock.Percentage Held by InsidersOnly 0.20% of the stock of Vertex Pharmaceuticals is held by insiders.Percentage Held by Institutions90.96% of the stock of Vertex Pharmaceuticals is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Vertex Pharmaceuticals' insider trading history. Receive VRTX Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Vertex Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. Email Address VRTX Stock News HeadlinesVertex Pharmaceuticals (NASDAQ:VRTX) Price Target Lowered to $490.00 at Truist FinancialAugust 6 at 3:41 AM | americanbankingnews.comBMO Capital Markets Has Lowered Expectations for Vertex Pharmaceuticals (NASDAQ:VRTX) Stock PriceAugust 6 at 3:41 AM | americanbankingnews.com[Shocking New Report] U.S. Dollar To Crash?The "Death Spiral" Threatening Your Savings But this time, it's not just Dalio ringing the alarm bells…August 6 at 2:00 AM | Goldco Precious Metals (Ad)Assessing Vertex Pharmaceuticals: Insights From 9 Financial AnalystsAugust 6 at 2:23 AM | benzinga.comThese Analysts Cut Their Forecasts On Vertex Pharmaceuticals After Q2 ResultsAugust 5 at 2:23 PM | benzinga.comThese Analysts Cut Their Forecasts On Vertex Pharmaceuticals After Q2 ResultsAugust 5 at 1:58 PM | benzinga.comVertex Pharmaceutical Stock Dives as Firm to Stop Developing Acute Pain DrugAugust 5 at 10:25 AM | investopedia.comVertex Pharmaceuticals (VRTX) Stock Dips After Pain Drug Trial SetbackAugust 5 at 5:30 AM | gurufocus.comSee More Headlines VRTX Stock Analysis - Frequently Asked Questions How have VRTX shares performed this year? Vertex Pharmaceuticals' stock was trading at $402.70 at the beginning of the year. Since then, VRTX shares have decreased by 6.9% and is now trading at $374.98. How were Vertex Pharmaceuticals' earnings last quarter? Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) announced its quarterly earnings results on Monday, August, 4th. The pharmaceutical company reported $4.52 EPS for the quarter, topping analysts' consensus estimates of $4.24 by $0.28. The company's revenue for the quarter was up 11.3% compared to the same quarter last year. Read the conference call transcript. Does Vertex Pharmaceuticals have any subsidiaries? The following companies are subsidiaries of Vertex Pharmaceuticals: V2X, Semma Therapeutics, Exonics Therapeutics, Aurora Biosciences Corporation, The Vertex Foundation Inc., Torreyana Insurance Company Inc., Vertex Farmaceutica do Brasil LTDA, and more. Who are Vertex Pharmaceuticals' major shareholders? Top institutional shareholders of Vertex Pharmaceuticals include Jennison Associates LLC (2.40%), Bank of New York Mellon Corp (0.62%), WCM Investment Management LLC (0.45%) and Sumitomo Mitsui Trust Group Inc. (0.26%). Insiders that own company stock include Reshma Kewalramani, Stuart A Arbuckle, Amit Sachdev, Ourania Tatsis, Charles F Wagner Jr, Bruce I Sachs, Bastiano Sanna, David Altshuler, Carmen Bozic, Edward Morrow Atkinson III, Jonathan Biller, Jeffrey M Leiden, Kristen Ambrose, Joy Liu, Sangeeta N Bhatia and Yuchun Lee. View institutional ownership trends. How do I buy shares of Vertex Pharmaceuticals? Shares of VRTX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Vertex Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Vertex Pharmaceuticals investors own include Salesforce (CRM), Chevron (CVX), QUALCOMM (QCOM), AbbVie (ABBV), Home Depot (HD), CocaCola (KO) and Bristol Myers Squibb (BMY). Company Calendar Last Earnings8/04/2025Today8/05/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryBiotechnology Current SymbolNASDAQ:VRTX CIK875320 Webwww.vrtx.com Phone(617) 341-6100Fax617-576-2109Employees6,100Year Founded1989Price Target and Rating Average Price Target for Vertex Pharmaceuticals$495.21 High Price Target$575.00 Low Price Target$405.00 Potential Upside/Downside+32.1%Consensus RatingModerate Buy Rating Score (0-4)2.50 Research Coverage26 Analysts Profitability EPS (Trailing Twelve Months)($3.92) Trailing P/E Ratio26.80 Forward P/E Ratio23.99 P/E GrowthN/ANet Income-$535.60 million Net Margins31.86% Pretax Margin-2.70% Return on Equity24.28% Return on Assets17.42% Debt Debt-to-Equity Ratio0.01 Current Ratio2.65 Quick Ratio2.29 Sales & Book Value Annual Sales$11.02 billion Price / Sales8.74 Cash FlowN/A Price / Cash FlowN/A Book Value$63.72 per share Price / Book5.88Miscellaneous Outstanding Shares256,800,000Free Float256,283,000Market Cap$96.29 billion OptionableOptionable Beta0.44 Social Links 7 Energy Stocks to Buy and Hold ForeverWith the proliferation of data centers and electric vehicles, the electric grid will only get more strained. 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