Marshall Wace, LLP Top Holdings and 13F Report (2021) About Marshall Wace, LLPInvestment ActivityMarshall Wace, LLP has $82.10 billion in total holdings as of September 30, 2021.Marshall Wace, LLP owns shares of 2,392 different stocks, but just 239 companies or ETFs make up 80% of its holdings.Approximately 47.34% of the portfolio was purchased this quarter.About 22.69% of the portfolio was sold this quarter.This quarter, Marshall Wace, LLP has purchased 2,428 new stocks and bought additional shares in 866 stocks.Marshall Wace, LLP sold shares of 869 stocks and completely divested from 626 stocks this quarter.Largest Holdings iShares Core S&P 500 ETF $13,359,728,020Microsoft $2,649,319,660Amazon.com $2,371,048,875Apple $2,118,458,368SPDR S&P 500 ETF Trust $1,718,525,952 Largest New Holdings this Quarter FERGUSON ENTERPR $289,485,473 HoldingSMURFIT WESTROCK $205,653,324 HoldingLPL Financial $200,818,777 HoldingBlackRock $132,336,057 HoldingDiamondback Energy $119,781,278 Holding Largest Purchases this Quarter Microsoft 6,155,213 shares (about $2.65B)Amazon.com 12,705,398 shares (about $2.37B)Apple 8,937,096 shares (about $2.08B)Meta Platforms 2,362,948 shares (about $1.35B)NVIDIA 10,506,718 shares (about $1.28B) Largest Sales this Quarter Spotify Technology 1,134,733 shares (about $418.18M)D.R. Horton 2,180,540 shares (about $415.98M)Lennar 1,769,567 shares (about $331.76M)Starbucks 3,340,413 shares (about $325.66M)Humana 981,971 shares (about $311.03M) Sector Allocation Over TimeMap of 500 Largest Holdings ofMarshall Wace, LLP Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorIVViShares Core S&P 500 ETF$13,359,728,020$373,779,360 ▲2.9%23,161,00016.3%ETFMSFTMicrosoft$2,649,319,660$2,648,588,150 ▲362,071.4%6,156,9133.2%Computer and TechnologyAMZNAmazon.com$2,371,048,875$2,367,396,807 ▲64,823.5%12,724,9982.9%Retail/WholesaleAAPLApple$2,118,458,368$2,082,343,368 ▲5,765.9%9,092,0962.6%Computer and TechnologySPYSPDR S&P 500 ETF Trust$1,718,525,952$1,128,969,192 ▲191.5%2,995,2002.1%FinanceMETAMeta Platforms$1,380,237,562$1,352,645,954 ▲4,902.4%2,411,1481.7%Computer and TechnologyNVDANVIDIA$1,305,433,610$1,275,935,834 ▲4,325.5%10,749,6181.6%Computer and TechnologyGOOGLAlphabet$1,162,527,898$1,157,071,433 ▲21,205.5%7,009,5141.4%Computer and TechnologySPYSPDR S&P 500 ETF Trust$1,071,057,299$481,500,539 ▲81.7%1,866,7341.3%FinanceTSLATesla$970,611,195$810,781,428 ▲507.3%3,709,8621.2%Auto/Tires/TrucksFLUTTER ENTER-DI$948,369,958$692,881,328 ▲271.2%3,996,8391.2%COMMON STOCKJNJJohnson & Johnson$854,300,426$224,703,483 ▲35.7%5,271,5071.0%MedicalLLYEli Lilly and Company$806,322,344$804,196,088 ▲37,822.2%910,1321.0%MedicalBSXBoston Scientific$690,555,494$127,379,269 ▲22.6%8,240,5190.8%MedicalAVGOBroadcom$569,846,854$564,275,104 ▲10,127.4%3,303,4600.7%Computer and TechnologyADBEAdobe$541,458,078$480,981,374 ▲795.3%1,045,7300.7%Computer and TechnologyGLDSPDR Gold Shares$484,491,498$429,765,324 ▲785.3%1,993,3000.6%FinanceACNAccenture$463,496,762$452,892,362 ▲4,270.8%1,311,2390.6%Computer and TechnologyGOOGAlphabet$453,389,019$450,296,004 ▲14,558.5%2,711,8190.6%Computer and TechnologyGE VERNOVA INC$438,597,730$155,731,841 ▼-26.2%1,720,1260.5%COMMON STOCKPFEPfizer$426,292,191$270,647,864 ▲173.9%14,730,2070.5%MedicalPGRProgressive$420,012,893$198,319,022 ▲89.5%1,655,1580.5%FinanceRACEFerrari$392,697,180$22,948,137 ▼-5.5%838,1300.5%Auto/Tires/TrucksDOORDASH INC-A$392,290,403$295,806,637 ▲306.6%2,748,4790.5%COMMON STOCKTMOThermo Fisher Scientific$388,296,803$387,863,804 ▲89,576.1%627,7330.5%MedicalGEGeneral Electric$387,094,394$73,967,299 ▼-16.0%2,052,6800.5%TransportationWDAYWorkday$379,714,640$191,685,629 ▲101.9%1,553,5970.5%Computer and TechnologyUNPUnion Pacific$363,845,150$49,774,911 ▼-12.0%1,476,1650.4%TransportationALCAlcon$352,758,075$48,772,919 ▲16.0%3,528,0350.4%MedicalORCLOracle$351,769,500$339,671,100 ▲2,807.6%2,064,3750.4%Computer and TechnologyVVisa$344,247,573$99,338,885 ▲40.6%1,252,0370.4%Business ServicesDHID.R. Horton$337,974,240$107,633,961 ▼-24.2%1,771,6320.4%ConstructionEFXEquifax$331,188,446$22,279,877 ▲7.2%1,127,0280.4%Business ServicesDKNGDraftKings$328,248,806$40,640,091 ▼-11.0%8,373,6940.4%Consumer DiscretionaryCRH PLC$317,853,459$134,611,275 ▲73.5%3,427,3610.4%COMMON STOCKRBLXRoblox$317,217,840$213,088,399 ▲204.6%7,167,1450.4%Consumer DiscretionaryELEstée Lauder Companies$305,911,126$108,217,582 ▲54.7%3,068,6240.4%Consumer StaplesDHRDanaher$304,546,167$226,052,780 ▼-42.6%1,095,4110.4%Multi-Sector ConglomeratesUBERUber Technologies$298,531,462$298,328,530 ▲147,009.1%3,971,9460.4%Computer and TechnologyANETArista Networks$293,311,790$98,242,951 ▲50.4%764,1910.4%Computer and TechnologyFERGUSON ENTERPR$289,485,473$289,485,473 ▲New Holding1,457,8510.4%COMMON STOCKAMDAdvanced Micro Devices$287,261,421$264,782,461 ▲1,177.9%1,750,7400.3%Computer and TechnologyUPSUnited Parcel Service$274,319,899$76,050,861 ▼-21.7%2,012,0280.3%TransportationJDJD.com$271,569,200$214,914,600 ▲379.3%6,789,2300.3%Retail/WholesaleABBVAbbVie$262,484,292$87,533,799 ▲50.0%1,329,1690.3%MedicalSHWSherwin-Williams$256,253,237$133,390,611 ▲108.6%671,4000.3%Basic MaterialsWMTWalmart$246,594,431$46,044,538 ▲23.0%3,053,8010.3%Retail/WholesaleEWEdwards Lifesciences$246,391,944$241,464,735 ▲4,900.6%3,733,7770.3%MedicalPDDPDD$241,109,302$218,825,209 ▲982.0%1,788,5120.3%Multi-Sector ConglomeratesCAVACAVA Group$240,758,333$188,669,871 ▲362.2%1,943,9510.3%Retail/WholesaleCMGChipotle Mexican Grill$238,266,134$101,977,202 ▼-30.0%4,135,1290.3%Retail/WholesaleNETCloudflare$234,672,808$109,411,813 ▲87.3%2,901,1350.3%Computer and TechnologyCOOPER COS INC$233,658,743$147,163,548 ▲170.1%2,117,6250.3%COMMON STOCKXLVHealth Care Select Sector SPDR Fund$231,030,000$198,154,123 ▲602.7%1,500,0000.3%ETFAMGNAmgen$227,193,816$196,197,214 ▲633.0%705,1110.3%MedicalWINGWingstop$222,064,806$193,355,286 ▲673.5%533,7070.3%Retail/WholesaleDBDeutsche Bank Aktiengesellschaft$219,102,675$136,440,843 ▲165.1%12,664,5590.3%FinanceURIUnited Rentals$215,115,301$93,532,722 ▲76.9%265,6630.3%ConstructionFTNTFortinet$214,017,527$269,805,756 ▼-55.8%2,759,7360.3%Computer and TechnologyHUBSHubSpot$213,566,577$85,154,877 ▲66.3%401,7430.3%Computer and TechnologyISRGIntuitive Surgical$212,587,758$176,269,641 ▲485.3%432,7310.3%MedicalNOCNorthrop Grumman$209,354,409$119,467,917 ▲132.9%396,4520.3%AerospaceTXNTexas Instruments$208,390,293$171,207,693 ▲460.5%1,008,8120.3%Computer and TechnologySMURFIT WESTROCK$205,653,324$205,653,324 ▲New Holding4,161,3380.3%COMMON STOCKLMTLockheed Martin$203,063,868$95,812,891 ▲89.3%347,3790.2%AerospaceLPLALPL Financial$200,818,777$200,818,777 ▲New Holding863,2540.2%FinanceOKTAOkta$196,661,115$27,634,259 ▲16.3%2,645,4280.2%Computer and TechnologyECLEcolab$196,472,859$5,555,981 ▼-2.8%769,4860.2%Basic MaterialsBKNGBooking$194,848,459$193,584,823 ▲15,319.7%46,2590.2%Retail/WholesaleIBKRInteractive Brokers Group$193,863,139$155,520,604 ▼-44.5%1,391,0960.2%FinanceTRUTransUnion$189,018,470$75,191,980 ▲66.1%1,805,3340.2%Business ServicesGRMNGarmin$187,025,714$6,333,207 ▼-3.3%1,062,4650.2%Computer and TechnologySFMSprouts Farmers Market$184,905,287$13,196,535 ▲7.7%1,674,7150.2%Retail/WholesaleSNOWSnowflake$181,141,342$148,601,504 ▲456.7%1,577,0620.2%Computer and TechnologyUNHUnitedHealth Group$180,492,471$178,913,835 ▲11,333.4%308,7030.2%MedicalBABAAlibaba Group$175,916,821$24,701,765 ▲16.3%1,657,7160.2%Retail/WholesaleHESHess$175,802,878$67,834,137 ▼-27.8%1,294,5720.2%Oils/EnergyMTBM&T Bank$174,942,873$54,401,054 ▲45.1%982,1630.2%FinanceNSCNorfolk Southern$171,546,517$16,498,661 ▲10.6%690,3280.2%TransportationILMNIllumina$161,677,494$64,691,185 ▲66.7%1,239,7630.2%MedicalRLRalph Lauren$160,657,937$48,413,023 ▲43.1%828,6890.2%Consumer DiscretionaryZTSZoetis$158,790,602$4,485,339 ▼-2.7%812,7270.2%MedicalICEIntercontinental Exchange$157,887,757$182,267,608 ▼-53.6%982,8670.2%FinanceBROSDutch Bros$157,411,496$30,496,659 ▲24.0%4,914,5020.2%Retail/WholesaleDGXQuest Diagnostics$155,353,245$126,007,113 ▲429.4%1,000,6650.2%MedicalHASHasbro$154,499,170$9,534,741 ▼-5.8%2,136,3270.2%Consumer DiscretionaryFUTUFutu$152,459,214$6,945,529 ▲4.8%1,593,9280.2%Business ServicesPINSPinterest$147,989,100$129,962,247 ▲720.9%4,571,7980.2%Computer and TechnologyCCChemours$144,616,507$2,175,988 ▲1.5%7,116,9540.2%Basic MaterialsTCOMTrip.com Group$144,144,257$42,921,060 ▲42.4%2,425,4460.2%Consumer DiscretionaryOXYOccidental Petroleum$143,283,727$142,278,697 ▲14,156.7%2,780,0490.2%Oils/EnergyCHWYChewy$143,173,824$58,442,512 ▲69.0%4,888,1470.2%Retail/WholesaleLYVLive Nation Entertainment$142,894,195$118,551,721 ▲487.0%1,305,0890.2%Consumer DiscretionaryCSXCSX$142,364,255$56,385,038 ▲65.6%4,122,9150.2%TransportationTECHBio-Techne$140,900,124$17,659,974 ▼-11.1%1,762,7940.2%MedicalREGNRegeneron Pharmaceuticals$140,870,365$78,980,712 ▲127.6%134,0040.2%MedicalHUMHumana$140,420,659$311,029,490 ▼-68.9%443,3310.2%MedicalDISWalt Disney$137,619,033$130,774,537 ▲1,910.7%1,430,7000.2%Consumer DiscretionaryCAHCardinal Health$136,806,520$134,581,642 ▲6,048.9%1,237,8440.2%MedicalSPOTSpotify Technology$136,290,134$418,183,155 ▼-75.4%369,8210.2%Business ServicesShowing largest 100 holdings. 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