Spyre Therapeutics (SYRE) Stock Chart & Stock Price History $21.29 -1.12 (-5.00%) Closing price 04:00 PM EasternExtended Trading$21.32 +0.03 (+0.12%) As of 07:33 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrends Spyre Therapeutics Stock Price Performance 5 Day Performance-8.26%1 Month Performance-5.63%3 Month Performance-22.13%6 Month Performance-20.87%Year-To-Date Performance-9.68%1 Year Performance+2.67% Receive SYRE Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address SYRE Stock Chart for Friday, February, 21, 2025 SYRE Chart by TradingView Spyre Therapeutics Stock Price History Daily Weekly Monthly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year Time Frame * Start Date * End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization02/20/2025$22.37$22.41+0.18%$23.04$21.63325,838 shs$1.15 billion02/19/2025$22.07$22.37+1.36%$22.55$21.92263,164 shs$1.15 billion02/18/2025$22.92$22.07-3.71%$23.60$21.61629,187 shs$1.14 billion02/17/2025$22.92$22.92$23.19$22.43462,061 shs$1.18 billion02/14/2025$22.68$22.92+1.06%$23.19$22.43462,061 shs$1.18 billion02/13/2025$23.27$22.68-2.54%$23.75$22.57509,443 shs$1.17 billion02/12/2025$22.15$23.27+5.06%$23.35$21.13467,868 shs$1.20 billion02/11/2025$22.75$22.15-2.64%$22.75$21.90993,051 shs$1.14 billion02/10/2025$22.65$22.75+0.44%$23.00$22.11709,262 shs$1.17 billion02/07/2025$23.86$22.65-5.07%$24.39$22.44682,957 shs$1.16 billion Get the Latest News and Ratings for SYRE and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 02/06/2025$23.56$23.86+1.27%$24.35$23.42477,741 shs$1.23 billion02/05/2025$23.70$23.56-0.59%$24.83$23.41405,297 shs$1.21 billion02/04/2025$22.90$23.70+3.49%$23.84$22.60645,349 shs$1.22 billion02/03/2025$22.99$22.90-0.39%$23.68$21.67508,624 shs$1.18 billion01/31/2025$22.27$22.99+3.23%$23.59$22.25557,455 shs$1.18 billion01/30/2025$21.90$22.27+1.69%$22.74$21.791.24 million shs$1.15 billion01/29/2025$21.79$21.90+0.50%$22.18$21.35330,139 shs$1.13 billion01/28/2025$20.82$21.79+4.66%$22.00$20.25533,004 shs$1.12 billion01/27/2025$21.60$20.82-3.61%$22.81$20.66501,573 shs$1.07 billion01/24/2025$21.81$21.60-0.96%$22.44$21.00437,241 shs$1.11 billion01/23/2025$21.82$21.81-0.05%$22.05$21.01532,132 shs$1.12 billion01/22/2025$22.28$21.82-2.06%$22.81$21.59651,476 shs$1.12 billion01/21/2025$20.62$22.28+8.05%$22.82$20.97692,673 shs$1.15 billion01/20/2025$20.62$20.62$21.24$20.33607,576 shs$1.06 billion Related Companies KRYS Stock Chart RARE Stock Chart RNA Stock Chart SWTX Stock Chart ADMA Stock Chart OGN Stock Chart BHVN Stock Chart ALVO Stock Chart PTCT Stock Chart ACLX Stock Chart Receive SYRE Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 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