Spyre Therapeutics (SYRE) Stock Chart & Stock Price History $12.67 +0.25 (+2.01%) Closing price 04/17/2025 04:00 PM EasternExtended Trading$12.60 -0.07 (-0.59%) As of 04/17/2025 04:32 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Spyre Therapeutics Stock Price Performance 5 Day Performance+3.68%1 Month Performance-29.26%3 Month Performance-38.55%6 Month Performance-61.32%Year-To-Date Performance-45.58%1 Year Performance-64.39% Receive SYRE Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address SYRE Stock Chart for Friday, April, 18, 2025 SYRE Chart by TradingView Spyre Therapeutics Stock Price History Daily Weekly Monthly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year Time Frame * Start Date * End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization04/17/2025$12.42$12.67+2.01%$12.79$12.25740,114 shs$763.46 million04/16/2025$12.71$12.42-2.28%$13.25$12.04573,432 shs$748.39 million04/15/2025$13.02$12.71-2.38%$13.29$12.57530,809 shs$765.87 million04/14/2025$12.22$13.02+6.55%$13.10$12.361.00 million shs$784.55 million04/11/2025$11.93$12.22+2.43%$12.87$11.50599,414 shs$736.34 million04/10/2025$13.37$11.93-10.77%$12.95$11.62978,765 shs$718.87 million04/09/2025$11.80$13.37+13.31%$13.76$10.911.03 million shs$805.64 million04/09/2025$11.80$13.37+13.31%$13.76$10.911.03 million shs$805.64 million04/08/2025$12.39$11.80-4.76%$13.28$11.461.52 million shs$711.03 million04/08/2025$12.39$11.80-4.76%$13.28$11.461.52 million shs$711.03 million Get the Latest News and Ratings for SYRE and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 04/07/2025$12.79$12.39-3.13%$13.23$11.601.28 million shs$746.58 million04/04/2025$13.99$12.79-8.58%$13.63$12.561.64 million shs$770.69 million04/03/2025$15.49$13.99-9.68%$15.02$13.88973,063 shs$843.00 million04/02/2025$15.30$15.49+1.24%$15.80$14.90586,262 shs$933.38 million04/01/2025$16.14$15.30-5.20%$16.12$15.241.27 million shs$921.93 million03/31/2025$17.94$16.14-10.03%$17.67$16.13740,838 shs$972.55 million03/28/2025$17.69$17.94+1.41%$18.28$17.39623,872 shs$1.08 billion03/27/2025$17.02$17.69+3.94%$17.92$16.71773,282 shs$1.07 billion03/26/2025$18.16$17.02-6.28%$18.78$16.93784,596 shs$1.03 billion03/25/2025$19.02$18.16-4.52%$19.50$17.55589,285 shs$1.09 billion03/24/2025$18.17$19.02+4.68%$19.40$17.97459,447 shs$1.15 billion03/21/2025$18.15$18.17+0.11%$18.54$17.541.30 million shs$1.09 billion03/20/2025$18.40$18.15-1.36%$18.65$18.03292,028 shs$1.09 billion03/19/2025$17.91$18.40+2.74%$18.82$17.79701,177 shs$1.11 billion03/18/2025$18.54$17.91-3.40%$19.00$17.86393,238 shs$1.08 billion03/17/2025$18.04$18.54+2.77%$18.91$18.07493,717 shs$1.12 billion Related Companies AKRO Stock Chart MRUS Stock Chart OGN Stock Chart MOR Stock Chart SWTX Stock Chart CRNX Stock Chart CPRX Stock Chart PTGX Stock Chart VKTX Stock Chart SRRK Stock Chart Receive SYRE Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Spyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 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