Upstream Bio (UPB) Stock Chart & Stock Price History $10.92 -0.22 (-1.97%) Closing price 07/16/2025 04:00 PM EasternExtended Trading$10.92 -0.01 (-0.05%) As of 07/16/2025 04:21 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Chart Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock Upstream Bio Stock Price Performance The Upstream Bio (UPB) stock chart highlights key performance trends across multiple timeframes. Since the beginning of the year, the stock decreased 33.58%. In the past month, the stock has increased 5.92%, reflecting recent market activity. As of the latest close, Upstream Bio traded at $10.92 with a market cap of $587.39 million and volume of 389,732 shares. 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Email Address 5 Day Performance-4.88%1 Month Performance+5.92%3 Month Performance+24.37%Year-To-Date Performance-33.58% UPB Stock Chart for Thursday, July, 17, 2025 UPB Chart by TradingView Upstream Bio Stock Price History Daily Weekly Monthly Yearly Time Frame Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year 3 Year 5 Year Time Frame Start Date End Date Export to Excel DateOpening PriceClosing PriceHighLowVolumeMarket Capitalization07/16/2025$11.14$10.92-1.97%$11.54$10.78389,732 shs$587.39 million07/15/2025$11.73$11.14-5.03%$11.89$11.11161,741 shs$599.27 million07/14/2025$11.48$11.73+2.18%$12.10$11.30261,127 shs$631.00 million07/11/2025$11.84$11.48-3.04%$11.85$11.45164,986 shs$617.56 million07/10/2025$11.70$11.84+1.20%$11.97$11.53410,864 shs$636.87 million07/09/2025$10.90$11.70+7.34%$11.84$10.92527,783 shs$629.34 million07/08/2025$10.98$10.90-0.73%$11.22$10.75207,281 shs$586.36 million07/07/2025$11.20$10.98-1.96%$11.47$10.83299,778 shs$590.61 million07/04/2025$11.20$11.20$11.49$11.08212,087 shs$602.49 million07/03/2025$11.13$11.20+0.63%$11.49$11.08212,087 shs$602.45 million Get the Latest News and Ratings for UPB and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. 07/02/2025$10.79$11.13+3.15%$11.32$10.60220,848 shs$598.68 million07/01/2025$10.98$10.79-1.73%$11.34$10.60243,195 shs$580.39 million06/30/2025$10.93$10.98+0.46%$11.50$10.91395,578 shs$590.61 million06/27/2025$10.94$10.93-0.09%$11.58$10.683.04 million shs$587.93 million06/26/2025$10.89$10.94+0.46%$11.27$10.76271,543 shs$588.46 million06/25/2025$11.39$10.89-4.39%$11.41$10.82276,201 shs$585.82 million06/24/2025$10.72$11.39+6.25%$11.55$10.60490,795 shs$612.67 million06/23/2025$10.88$10.72-1.47%$11.15$10.41526,559 shs$576.63 million06/20/2025$10.64$10.88+2.26%$11.61$10.64798,298 shs$585.28 million06/19/2025$10.64$10.64$10.72$9.82605,747 shs$572.33 million06/18/2025$10.31$10.64+3.20%$10.72$9.82605,747 shs$572.33 million06/17/2025$11.17$10.31-7.70%$11.31$10.10521,114 shs$554.62 million06/16/2025$11.36$11.17-1.67%$11.46$10.74264,020 shs$600.88 million Related Companies ARWR Stock Price Chart GMTX Stock Price Chart APLS Stock Price Chart NAMS Stock Price Chart TWST Stock Price Chart RXRX Stock Price Chart DNLI Stock Price Chart INDV Stock Price Chart AGIO Stock Price Chart BEAM Stock Price Chart Receive UPB Stock News and Ratings via EmailSign-up to receive the latest news and ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. 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